The antibacterial activity of photodynamic agents against multidrug resistant bacteria causing wound infection

Ayşe Akbiyik,Hüseyin Taşli,Nermin Topaloğlu,Vildan Alptüzün,Sülünay Parlar,Selçuk Kaya

Photodiagnosis and Photodynamic Therapy（2022）

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摘要

•CPD was synthesized by the researchers as a photosensitizer.•Decreases of up to 5.80-6.78 log...... occurred in aPDT, depending on the type of MDR bacteria.•The cytotoxic effect of PL and PM on fibroblast cells was very limited.•The best result was observed in aPDI application with PL.•Among the photosensitizers, it was PL with high antimicrobial activity and limited cytotoxicity.

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关键词

Antimicrobial photodynamic inactivation,Cationic porphyrin derivatives,Pseudomonas aeruginosa,Escherichia coli,Acinetobacter baumannii,Klebsiella pneumoniae

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