Stimulation of naïve B cells with a fusion protein consisting of FlaA and Bet v 1 induces regulatory B cells ex vivo

Alexandra Goretzki,Yen‐Ju Lin,Clara Meier,Britta Dorn,Sonja Wolfheimer,Annette Jamin, Maike Schott,Andrea Wangorsch,Stefan Vieths,Thilo Jakob,Stephan Scheurer,Stefan Schülke

Allergy（2022）

引用 5|浏览13

暂无评分

摘要

rFlaA:Betv1 can act as a thymus-independent B cell antigen, stimulating the mTOR- and MyD88-dependent differentiation of B cells displaying a regulatory phenotype, IL-10 secretion, antigen-binding antibody production, and a suppressive capacity in vitro.

查看译文

关键词

AIT,MyD88,flagellin,regulatory B cell,vaccine

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要