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Normal Sperm DNA Integrity in Patients With Inflammatory Bowel Disease on Ustekinumab Maintenance Therapy

Anne Grosen,Emanuelle Bellaguarda,Ingela Liljeqvist-Soltic,Mette Mejlby Hansen,Anne-Bine Skytte,Mette Julsgaard,Stephen B Hanauer,Jens Kelsen

INFLAMMATORY BOWEL DISEASES（2022）

Cited 2|Views14
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Abstract
Lay Summary We demonstrate that ustekinumab does not adversely affect semen quality or sex hormones in male patients. Ustekinumab is not detectable in semen and poses no risk to partners. Our observations support a recommendation to continue ustekinumab therapy in patients wishing to conceive.
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Key words
inflammatory bowel disease, ustekinumab, sperm DNA integrity
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