Widespread exposure to Crimean-Congo haemorrhagic fever in Uganda might be driven by transmission from Rhipicephalus ticks: Evidence from cross-sectional and modelling studies

•Crimean-Congo haemorrhagic fever (CCHF) is a major public health concern throughout Africa.•We did a cross-sectional study at three urban abattoirs receiving cattle from across Uganda.•CCHF virus seropositivity was high in humans (10.3%) and cattle (69.7%), and viral antigen was present in ticks (mainly Rhipicephalus appendiculatus).•Ecological modelling predicted high human CCHF risk across much of Uganda.•Predicted environmental suitability was low for Hyalomma, but high for Rhipicephalus and Amblyomma ticks.