GALIPDIA study: Reaching lipid targets in a population with type 2 diabetes (T2DM) from the Northwest of Spain

ENDOCRINOLOGIA DIABETES Y NUTRICION(2023)

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Abstract
Aim: To assess the degree of compliance with the European ESC/EAS 2016 and 2019 dyslipi-daemia guidelines in patients with type 2 diabetes mellitus (T2DM). Methods: Multicentre retrospective cross-sectional study, conducted in 380 adults with T2DM and dyslipidaemia in 7 Spanish health areas. Inclusion criteria: minimum follow-up of one year in Endocrinology Units, at least one visit in 2020 and a lipid profile measurement in the last 3 months. Exclusion criteria: familial hypercholesterolaemia, recent hospitalisation, active oncological pathology and dialysis. Results: According to the 2016 and 2019 guidelines the majority of patients were classified as being at very high cardiovascular risk (86.8% vs. 72.1%, respectively). LDL-c compliance was adequate in 62.1% of patients according to the 2016 guidelines and 39.7% according to the 2019 guidelines (p < 0.001). Clinical conditions such as history of cardiovascular disease and therapy -related aspects (use of statins, especially high-potency statins, combination therapies and good adherence) were significantly associated with greater achievement of lipid targets. Conclusion: There is a discrepancy between dyslipidaemia guideline recommendations and the reality of lipid control in patients with T2DM, despite most of these patients being at very high cardiovascular risk. Strategies to optimise lipid-lowering treatments need to be implemented. (c) 2022 SEEN y SED. Published by Elsevier Espana, S.L.U. All rights reserved.
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Key words
Cardiovascular risk,Type 2 diabetes mellitus,Guidelines,Dyslipidaemia,Cholesterol
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