Evaluation of Clinical and Radiological Tumour Response during Neo-Adjuvant Breast Cancer Chemotherapy at Yalgado Ouedraogo University Hospital

Advances in Breast Cancer Research(2022)

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摘要
Background: Neoadjuvant chemotherapy (NAC) is one of the treatment options for breast cancer.Its aim is to significantly reduce the size of the tumour in preparation for surgery.The aim of this work is to analyze the conditions of clinical and radiological evaluation of NAC at the Yalgado Ouédraogo University Hospital (CHUYO).Patients and Methods: This was a descriptive cross-sectional study based on the medical records of patients followed up in the cancer department of the CHUYO from 1 January 2013 to 31 December 2021.All patients followed for histologically proven, non-metastatic breast cancer and having received at least one course of NAC were included in this study.The variables were related to the socio-demographic characteristics of the patients, the indications, the protocols of NAC and the sequences of evaluation of the tumour response (clinical, radiological and anatomopathological). Results: We collected 105 cases.The average age of the patients concerned was 44 years.The most frequent histological type was non-specific invasive carcinoma in 97.1% of cases.Immunohistochemically, triple-negative patients accounted for 51.4%.At the initial stage, all patients underwent clinical exploration.Clinical measurement of the tumour was performed in 70.5% of cases.The radiological size of the tumour was determined by ultrasound in
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breast cancer,cancer chemotherapy,radiological tumour response,neo-adjuvant
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