Pharmacist-Driven Therapeutic Infliximab Monitoring at the Point of Care Using Rapidly Assessed Drug Levels in Patients with Inflammatory Bowel Disease.

Clarissa A Rentsch,Mark G Ward,Raphael P Luber,Kirstin M Taylor,David J Gibson,Belinda Headon,Ourania Rosella,Heidi Y Su,Antony B Friedman,Michael Dooley,Miles P Sparrow,Peter R Gibson

Therapeutic drug monitoring（2023）

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摘要

Immediate dose adjustment after infliximab rapid assay performed by a pharmacist using a sliding scale is a feasible strategy. Supratherapeutic infliximab levels can be safely and quickly brought into the therapeutic range using small dose adjustments without affecting disease activity, offsetting (at least partly) costs associated with dose escalation.

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关键词

infliximab, rapid test, proactive, therapeutic drug monitoring, Crohn disease, ulcerative colitis, pharmacist-driven intervention

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