Experimental Study of Selective MGMT Peptides Mimicking TMZ Drug Resistance in Glioma

Yue Wu,Youxin Zhou,Kai Zhang,Hao Wang,Guangliang Chen, Wen Li,Yongsheng Liu

SSRN Electronic Journal（2022）

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摘要

The results of this study indicate that MGMT-02 and MGMT-04 peptides have a role in glioma resistance and that MGMT peptides may serve as a precise target for TMZ-resistant GBM.

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关键词

Apoptosis,Drug resistance,Glioblastoma multiforme,O6-methylguanine-DNA methyltransferase (MGMT),Peptides,Temozolomide (TMZ)

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