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Invasion and Metastasis Suppression by Anti-Neonatal Nav1.5 Antibodies in Breast Cancer.

Nur Aishah Sharudin,Ahmad Hafiz Murtadha Noor Din,Irfan Irsyad Azahar, Mawaddah Mohd Azlan,Nik Soriani Yaacob,Maria Elena Sarmiento,Armando Acosta Dominguez,Noor Fatmawati Mokhtar

Asian Pacific journal of cancer prevention : APJCP（2022）

Cited 2|Views6
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Abstract
Overall, this work verifies the uniqueness of targeting nNav1.5 in breast cancer invasion and metastasis prevention, but more importantly, humanised versions of mAb-nNav1.5 may be valuable passive immunotherapeutic agents to target nNav1.5 in breast cancer.
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Key words
Monoclonal antibody,Polyclonal antibody,Voltage-gated sodium channel,breast cancer,nNav1.5
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