TACE/ADAM17 substrates associate with ACS (Ep-CAM, HB-EGF) and follow-up MACE (TNFR1 and TNFR2).

Melody Chemaly,Roisin McAllister,Aaron Peace,Anthony John Bjourson, Steve Watterson,Andrew Parton,Matthias Clauss,Victoria McGilligan

Atherosclerosis plus（2022）

引用 1|浏览13

暂无评分

摘要

We demonstrate a possible role of TACE substrates LAG-3, HB-EGF and Ep-CAM in atherosclerotic plaque development and stability. We also underline the importance of measuring TNFR1 and TNFR2 earlier than previously appreciated for MACE prediction. We report an important role of TIMP3 in regulating TACE levels.

查看译文

关键词

Acute coronary syndrome,Coronary artery disease,Major adverse cardiovascular events,Tumour necrosis factor alpha converting enzyme TACE/ADAM17

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要