Diurnal rhythms of spontaneous intracranial high-frequency oscillations

Gabrielle T. Petito,Jeremy Housekeeper,Jason Buroker,Craig Scholle,Brian Ervin,Clayton Frink,Hansel M. Greiner,Jesse Skoch,Francesco T. Mangano,Thomas J. Dye,John B. Hogenesch,Tracy A. Glauser,Katherine D. Holland,Ravindra Arya

Seizure（2022）

引用 2|浏览24

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摘要

•Intracranial high-frequency oscillations (HFOs) show a significant diurnal rhythm.•Diurnal rhythm of HFOs is relatively attenuated within the seizure-onset zone (SOZ).•Peak difference in HFO density within/outside SOZ consistently precedes seizures.•Difference in HFO density within/outside SOZ peaks at 1st hour after arousal and ±2 hours around sleep onset.

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关键词

Circadian rhythms,Chronobiology,Cosinor model,Stereo-EEG,Drug-resistant epilepsy

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