A genome-wide association study to investigate genetic loci associated with primary glaucoma in American Cocker Spaniels.

Filipe Espinheira Gomes,Maria Isabel Casanova,Lara Mouttham,Danika L Bannasch,Sangwan Park,Soohyun Kim,Laura J Young,Nicole L Daley,Sara M Thomasy,Marta G Castelhano,Eric C Ledbetter, Bradford Holmberg, Ryan Boyd, Alexandra Van Der Woerdt, Jessica McDonald,Jessica J Hayward

American journal of veterinary research（2022）

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摘要

Primary glaucoma in the American Cocker Spaniel is a complex heterogeneous disease that may be influenced by a locus on CFA10. The candidate genes CCDC85A and EFEMP1 within the identified linkage disequilibrium interval have been shown to be involved in human open-angle glaucoma.

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关键词

genetic loci,primary glaucoma,american cocker spaniels,genome-wide

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