Telomeres are a life-extending gift
NATURE CELL BIOLOGY（2022）
摘要
Cellular senescence induced by DNA replication and telomere attrition contributes to organ dysfunction, inflammation and impaired immunity. A study reveals that antigen-presenting cells provide telomeric DNA to CD4 + T cells in synaptic contact, which enables the suspension of senescence, T cell expansion and long-lived immunity.
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关键词
Senescence,T cells,Telomeres,Life Sciences,general,Cell Biology,Cancer Research,Developmental Biology,Stem Cells
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