Possible anti-inflammatory, antioxidant, and neuroprotective effects of apigenin in the setting of mild traumatic brain injury: an investigation.

Pınar Kuru Bektaşoğlu,Dilan Demir,Türkan Koyuncuoğlu,Meral Yüksel,İrem Peker Eyüboğlu,Ayça Karagöz Köroğlu,Dilek Akakın,Alper Yıldırım,Erhan Çelikoğlu,Bora Gürer

Immunopharmacology and Immunotoxicology（2023）

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摘要

The results of this study revealed that apigenin 20 and 40 mg treatment may have neuroprotective effects in mild TBI via decreasing the level of luminol and lucigenin and increasing the IL-10 levels. Additionally, apigenin 20 mg treatment ameliorated the trauma-induced cortical tissue damage.

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Apigenin,inflammation,neuroprotection,oxidative stress,traumatic brain injury

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