Chrome Extension
WeChat Mini Program
Use on ChatGLM
VIPCreated with Sketch.

A Novel B7-H6-Targeted IgG-Like T Cell-Engaging Antibody for the Treatment of Gastrointestinal Tumors.

Wei Zhang,Aurélie Auguste, Xiaoyun Liao,Christian Walterskirchen,Kathrin Bauer,Yu-Hsi Lin, Ling Yang, Farzaneh Sayedian,Markus Fabits,Michael Bergmann,Carina Binder,Leticia Corrales,Anne B Vogt, Lindsey J Hudson, Martin P Barnes,Arnima Bisht,Craig Giragossian,Vladimir Voynov,Paul J Adam,Susanne Hipp

Clinical cancer research : an official journal of the American Association for Cancer Research（2022）

Cited 6|Views28
No score
Abstract
These data highlight the potential of the B7-H6/CD3 ITE to induce T cell-redirected lysis of tumor cells and recruitment of T cells into noninflamed tumor tissues, leading to antitumor activity in in vitro, in vivo, and human tumor slice cultures, which supports further evaluation in a clinical study.
More
Translated text
Key words
antibody,gastrointestinal tumors,igg-like
AI Read Science
Must-Reading Tree
Example
Generate MRT to find the research sequence of this paper
Chat Paper
Summary is being generated by the instructions you defined