Post-contrast MRI in multiple sclerosis: Towards a judicious use of gadolinium-based contrast agents

We thank the authors of the Letter entitled “Should we stop using post-contrast sequences in the follow-up MRI of patients with multiple sclerosis?” for having appreciated and commented on our work “Impact of post-contrast MRI in the definition of active multiple sclerosis” [1]. The issue of gadolinium (Gd) administration in people with MS (PwMS) is still under debate. Post-Gd MRI sequences certainly provide useful diagnostic and prognostic information, predicting treatment response and long-term disability [2,3]: such aspects were clearly presented in the Discussion section of our study [1].