A plant‐derived glucocorticoid receptor modulator with potency to attenuate the side effects of glucocorticoid therapy

Yixuan Wang,Jian Gao, Ying Yu,Lin Zhou, Miao Wang,Wenwen Xue,Bo Liu,Xudong Wu,Xuefeng Wu,Huiyuan Gao,Yan Shen,Qiang Xu

British Journal of Pharmacology（2022）

引用 3|浏览15

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摘要

Our results reveal that CA-e is a novel GR modulator with strong potency to attenuate the side effects of GC therapy and can be used as a potential molecular tool for deciphering GR signalling.

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关键词

EED,ant-inflammation,caesaldekarin e,dimerization,glucocorticoid receptor,side effects

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