[VCR, a Small Molecule Compound, Induces Reprogramming of Rat Fibroblasts into Neural Progenitor Cells under Hypoxic Condition].
Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition（2022）
Abstract
Our study demonstrates that VCR, a small molecule compound, can directly induce, under a hypoxic condition, the reprogramming of REFs to form ciRNPCs with the potential to be induced for differentiation into glial cells and neurons and , laying the foundation for transplanting ciRNPCs to treat neurodegenerative diseases.
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Key words
Cell reprogramming,Hypoxia,Neural progenitor cells,Small molecule compounds
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