A Complex of Silver(I) with N-O Chelating Agent and Phosphine Ligand: Design, Structures, and Biological Activity

A new Ag(I) complex, [Ag(Qina) (Tpp)(2)]center dot 1.5H2O (Qina=2 - quinolinecarboxylate, Tpp=triphenylphosphine), was synthesized and successfully obtained as a single crystal. The structure of the complex was characterized by single-crystal X-ray diffraction, IR, NMR, and powder X-ray diffraction. The results show that the complex belongs to monoclinic crystal system, C2/c space group, and the unit cell parameters are a=3.195 90(13) nm, b= 1.210 96(4) nm, c=2.319 74(7) nm, beta=102.166(4)degrees, V=8.776 0(5) nm(3), and Z=8. The supramolecular structures and weak intermolecular force of the complex were deduced by Hirshfeld surface analysis. Meanwhile, the biological activities of the complex were tested by evaluating DNA - binding efficacy, antibacterial activity, and in vitro toxic activity of cancer cells.