Chop-Chop: The Future of Bacterial Enzymes in Transfusion Medicine

Transfusion Medicine Reviews（2022）

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摘要

•Bacterial enzymes rapidly degrade antibodies for treatment of autoimmune disease.•Imlifidase (IdeS) is a first-in-class medication advancing through clinical trials.•Current research is focused on desensitization for kidney transplantation, anti-GBM disease, antibody-mediated rejection, and Guillain-Barré syndrome.

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关键词

Imlifidase,IdeS,EndoS,Antibody desensitization,Transplant,Anti-GBM,Goodpasture,TTP

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