Interaction of TNFi and conventional synthetic DMARD in SARS-CoV-2 vaccine response in axial spondyloarthritis and psoriatic arthritis

Joint Bone Spine(2023)

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摘要
•TNF inhibitors attenuate humoral response to SARS-CoV-2 vaccine in SpA patients.•Sulfasalazine has a positive impact on vaccine antibody production.•Vaccine humoral response was comparable between SpA patients without current DMARD/prednisone and control group.•Pre-vaccination disease activity status did not influence humoral response.
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关键词
Ankylosing spondylitis,Psoriatic arthritis,COVID-19,Vaccination,Therapeutics and TNFi
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