Deregulation of PRDM5 promotes cell proliferation by regulating JAK/STAT signaling pathway through SOCS1 in human lung adenocarcinoma.

Yuanyuan Ren,Ye Wang,Lijiao Fang,Mengchu Ma,Lin Ge,Chao Su,Lingbiao Xin,Jinyan He,Jie Yang,Xin Liu

Cancer medicine（2023）

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摘要

Our study suggests that the low expression of PRDM5 promotes the proliferation of lung adenocarcinoma cells by downregulating SOCS1 and then upregulating the JAK2/STAT3 signaling pathway.

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关键词

JAK/STAT signaling pathway,PRDM5,SOCS1,lung adenocarcinoma

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