Biases in reporting of adverse effects in clinical trials, and potential impact on safety assessments in systematic reviews and therapy guidelines.

Tone Westergren,Sigrid Narum,Marianne Klemp

Basic & clinical pharmacology & toxicology（2022）

引用 1|浏览2

暂无评分

摘要

We identified several pitfalls in adverse effects reporting in clinical trials. These include heterogeneous disease definitions, reporting thresholds, and incomplete reporting. Trial bias may have great impact on risk assessments in systematic reviews and meta-analyses.

查看译文

关键词

adverse drug reactions,antidepressants,corticosteroids,randomized controlled trials,systematic reviews,therapy guidelines

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要