MDS-431 Outcomes of Transformation to Acute Myeloid Leukemia after Hypomethylating Agent Therapy in Patients With Myelodysplastic Syndromes

Kunhwa Kim,Faustine Ong,Ziyi Li,Rashmi Kanagal Shamanna,Guillermo Montalban Bravo,Tapan Kadia,Elias Jabbour,Naveen Pemmaraju,Danielle Hammond,Nicholas Short,Farhad Ravandi,Yesid Alvarado,Sherry Pierce,Xiao Qin Dong,Hagop Kantarjian,Guillermo Garcia-Manero,Kelly Chien

Clinical Lymphoma Myeloma and Leukemia（2022）

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摘要

The outcomes of AML transformation after HMA failure MDS remain extremely poor. Further understanding of the biology and disease characteristics of this patient population is warranted for better treatment approaches.

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关键词

MDS,hypomethylating agent,hypomethylating agent failure,AML

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