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Level of Amyloid-β (Aβ) Binding Leading to Differential Effects on Resting State Functional Connectivity in Major Brain Networks.

Eva Y W Cheung,Anson C M Chau,Yat-Fung Shea, Patrick K C Chiu, Joseph S K Kwan,Henry K F Mak

Biomedicines(2022)

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摘要
The level of Aβ accumulated demonstrated differential effects on IFC in various brain networks. As the treatment to reduce Aβ plaque deposition is available in the market, it may be an option for the HiAmy group to improve their IFC in major brain networks.
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关键词
18F-flutemetamol,Alzheimer’s disease,Amyloid-β protein (Aβ),central executive network (CEN),default mode network (DMN),mild cognitive impairment,resting state functional MRI (rsMRI),salience network (SN),self-referential network (SRN),sensory motor network (SMN),vascular dementia
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