Antibody Optimization Enabled by Artificial Intelligence Predictions of Binding Affinity and Naturalness
Sharrol Bachas,Goran Rakocevic,David Spencer,Anand V. Sastry, Robel Haile,John M. Sutton,George Kasun,Andrew Stachyra,Jahir M. Gutierrez,Edriss Yassine, Borka Medjo,Vincent Blay,Christa Kohnert, Jennifer T. Stanton,Alexander Brown,Nebojsa Tijanic,Cailen McCloskey,Rebecca Viazzo,Rebecca Consbruck,Hayley Carter, Simon Levine,Shaheed Abdulhaqq, Jacob Shaul,Abigail B. Ventura,Randal S. Olson,Engin Yapici,Joshua Meier, Sean McClain, Matthew Weinstock,Gregory Hannum,Ariel Schwartz,Miles Gander,Roberto Spreafico biorxiv(2022)
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