Human galectin-9 promotes the expansion of HIV reservoirs in vivo in humanized mice.

Zhe Yuan,Leila B Giron,Colin Hart, Akwasi Gyampoh,Jane Koshy,Kai Ying Hong,Toshiro Niki,Thomas A Premeaux,Lishomwa C Ndhlovu,Claire Deleage,Luis J Montaner,Mohamed Abdel-Mohsen

AIDS (London, England)（2023）

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摘要

Our study highlights the overall adverse effects of Gal-9 on HIV persistence and the potential need to block Gal-9 interactions during ART-suppressed HIV infection.

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关键词

bone marrow, liver, thymus mice, galectin-9, HIV, HIV reservoirs, humanized mice

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