2-(Aminomethyl)phenols-Modified Boehmite Nanoparticles Based Catalysts for Carbon–Carbon Bond Formation Reactions

A Pd nanoparticles supported on 2-(aminomethyl)phenols modified boehmite was prepared by a simple and rapid method. This material is characterized by various technique to confirm its microstructure, and also employed as a recyclable catalyst for Suzuki–Miyaura cross-coupling reaction with high reactivity. Meanwhile, the 2-(aminomethyl)phenols modified boehmite performed well as a catalyst in the Konevenagel condensation reactions to construct a variety of structural diverse α-cyano-substituted alkenes with up to 99% yield. Moreover, these catalysts can be easily separated from the reaction system, and continuous reuse for six times without significant loss of catalytic efficiency. In addition, we proved the hydroxyl group in the o-aminomethyl phenol motif plays a vital role in these processes. Graphical Abstract A 2-(aminomethyl)phenols modified boehmite composite material has been prepared as efficient catalyst for Konevenagel condensation and the Pd nanoparticles supported on this material showed good activity and generality in Suzuki–Miyaura reactions.