Gentle Touch Therapy, Pain Relief and Neuroplasticity at Baseline in Fibromyalgia Syndrome: A Randomized, Multicenter Trial with Six-Month Follow-Up.

Afonso Shiguemi Inoue Salgado, Miriam Hatsue Takemoto, Carla Fernanda Tallarico Carvalho de Souza,Daiana Cristina Salm, Danielli da Rosa, Gabriela Correa Cardoso,Daniela Dero Ludtke, Silvia Fiorillo Cabrera Soares,Júlia Koerich Ferreira,Aline Raulino Dutra, Yuri Cordeiro Szeremeta,Gustavo Mazzardo, Joice Mayra, Débora da Luz Sheffer,Wolnei Caumo,Edsel B Bittencourt,Robert Schleip,Alexandra Latini,Franciane Bobinski,Daniel Fernandes Martins

JOURNAL OF CLINICAL MEDICINE（2022）

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摘要

In conclusion, lower pain scores were observed in the GTT group compared to the placebo group without altering the quality of life in women with FM. Reductions in BDNF levels could be a mechanism of FM pain status improvement. In this sense, the present study encourages the use of these GTT techniques as an integrative and complementary treatment of FM.

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关键词

chronic pain,inflammatory biomarkers,manual therapy,neurotransmitter systems,osteopathic treatment

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