A system of co-immobilized dual-enzyme and coenzyme for in-situ coenzyme regeneration

Yuefeng Deng,Yihui Zhu, Zhenni Jiao,Ziqian Chen,Jianjun Wang,Chengli Yang,Dali Li,Kefeng Ma,Ruofu Shi

Molecular Catalysis（2022）

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摘要

•A co-immobilization system of dual-enzyme and coenzyme was successfully constructed.•The immobilized enzymes presented improved stability and fine reusability.•The system realized chiral (R)−1-phenylethanol highly selective production and coenzyme effective recycling.

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关键词

Coenzyme regeneration,(R)-1-phenylethanol,Magnetic nanoparticles,Recombinant GDH,Click chemistry

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