Solution blow spinning polysulfone-Aliquat 336 nanofibers: synthesis, characterization, and application for the extraction and preconcentration of losartan from aqueous solutions

Nanofibers are materials used in a wide range of applications due to their unique physicochemical properties. As an alternative to the most common method of its manufacturing (electrospinning) blow spinning has been used since it has greater production efficiency and simplicity. A wide variety of polymers is used for its preparation and can be modified to improve the interaction and selectivity toward specific analytes. Thereby nanofibers have been used for the extraction or removal of organic compounds such as drugs but there are still few reports of drug extractions like losartan. In this work polysulfone-Aliquat 336 nanofibers were prepared using the blow spinning method to extract and preconcentrate losartan. The studies showed that Aliquat 336 incorporation significantly improve the extraction of losartan with polysulfone fibers. Adsorption process was thermodynamically favorable with an adsorption capacity of 15.45 mg center dot g(-1). Thus, it was possible to extract more than 92% of initial losartan using 10 mg of polysulfone-Aliquat 336 fibers (9 and 3.5% (w/v)), at pH 6 from deionized water and synthetic wastewater. Finally, losartan preconcentration was evaluated to facilitate its quantification using ultraviolet-visible spectrometry (UV-Vis), which allowed the determination of this drug at concentrations below the detection limit.