Prediction of Biochemical Recurrence Based on Molecular Detection of Lymph Node Metastasis After Radical Prostatectomy

Berna C. Özdemir,Nicolas Arnold,Achim Fleischmann,Janine Hensel,Irena Klima,Marianna Kruithof-de Julio,Fiona Burkhard,Stefanie Hayoz,Bernhard Kiss,George N. Thalmann

European Urology Open Science（2022）

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摘要

Our study shows that molecular detection of lymph node micrometastases with a panel of prostate epithelial markers seems to be more useful for early detection of biochemical recurrence than histology alone or using markers of stem cells, epithelial-to-mesenchymal transition, or reactive stroma.

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关键词

Prostate cancer,Lymph nodes,Metastasis,Extended lymphadenectomy,Micrometastasis,Isolated tumor cells,Molecular detection,Molecular markers,mRNA expression

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