The Trace Gas Monitoring Method Based on Diode Laser Wavelength-Modulation Spectroscopy Technology for the Detection of Clinical Blood Infection

It is important to monitor and evaluate the growth of microorganisms in order to accurately judge the situation of blood microbial infection. In this paper, diode laser wavelength modulation spectroscopy (DLWMS) technology is used to design a set of low-cost, high sensitivity, fast dynamic responses and a non-invasive trace gas measurement system, which can quickly and accurately assess the concentration of carbon dioxide (CO2) produced by blood microbial reproduction. The measurement principle and spectral processing algorithm of DLWMS are introduced first. The automatic and rapid detection of CO2 is realized through a self-designed optical system. By using the system to detect blood infection, the accuracy of the technology was verified. Therefore, it also indicates that DLWMS CO2 monitoring is a highly sensitive, fast-response and non-invasive technology, which can accurately and quickly determine blood infection and meet the clinical application requirements of human septicemia, bacteremia and other diseases.