Stabilization to a cancer invasion model with remodeling mechanism and slow diffusion

In this paper, we consider the stability of solutions to a class of cancer invasion model. This kind of model was first proposed by Chaplain and Lolas in 2005. In fact, they proposed two kinds of tumor invasion models in 2005 (Chaplain and Lolas in Math Models Methods Appl Sci 15(11):1685–1734, 2005) and 2006 (Chaplain and Lolas in Netw Heterog Media 1(3):399–439, 2006), respectively, which have similar structures, but their solutions have different properties. For convenience of distinction, we call them Model I and Model II, respectively. A common feature of the two models is that they both consider the remodeling of extracellular matrix. For the research on the stability of solutions of the two models, there are only the three papers (Hillen in Math Models Methods Appl Sci 23(01):165–198, 2013; Tao in SIAM J Math Anal 47(6): 4229–4250, 2015; Wang in J Differ Equ 260(9):6960–6988, 2016) on Model II by removing the remodeling of extracellular matrix, and the paper (Jin in Nonlinearity 33(10):5049–5079, 2020) on Model I. However, as far as we know, although the existence of solutions of this kind of model with porous medium diffusion has achieved fruitful results, there are no relevant results on stability even without considering the remodeling effect of extracellular matrix. In the present paper, we consider the stability of this kind of model with nonlinear diffusion, we find that the simultaneous emergence of haptotaxis, nonlinear diffusion and remodeling effect does bring essential difficulties to the study of stability, such as the method of constructing Lyapunov functional is no longer applicable. In this paper, we use some detailed analytical techniques to prove the global asymptotic stability of bounded solutions.