Aspergillines K and L, Two New Anti-TMV Indole Alkaloids from Fungus Aspergillus versicolor Derived from Tobacco

Two new ( 1 and 2 ) and four known ( 3 – 6 ) CPA-type indole alkaloids were isolated from the fungus Aspergillus versicolor . Their structures were determined by means of HR-ESI-MS and extensive 1D and 2D NMR spectroscopic studies. Compounds 1 and 2 were tested for their anti-tobacco mosaic virus (anti-TMV) activity. The results showed that compounds 1 and 2 demonstrated potential anti-TMV activity with inhibition rates within the range 29.2 and 30.1% respectively.