Houttuynia cordata polysaccharide alleviates chronic vascular inflammation by suppressing calcium-sensing receptor in rats
Journal of Functional Foods（2022）
Abstract
•Houttuynia cordata polysaccharide (HCP) attenuated vascular injury in the rat model of chronic inflammation.•HCP platformed vascular protection in parallel with inhibition of oxidative stress and inflammation.•Vascular protection of HCP ameliorated chronic vascular inflammation via the TLR4/NF-kB pathway.•Anti-inflammatory responses of HCP were linked to suppress calcium-sensing receptor.
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Key words
Houttuynia cordata polysaccharide,Chronic inflammation,Blood vessel,Oxidative stress,Calcium sensitive receptor
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