Chrome Extension
WeChat Mini Program
Use on ChatGLM

Green hemi-synthesis of novel thiazole derivatives from Ammodaucus leucotrichus Coss. & Dur. and Cuminum cyminum L. essential oils: stereochemistry, molecular fluorescence spectroscopy, in vitro biologicial activity, and molecular docking study

Journal of Molecular Structure(2022)

Cited 4|Views6
No score
Abstract
•New thiazole derivatives from natural product (Ammodaucus leucotrichus and Cuminum cyminum) were hemi-synthesized.•Chemical characterization of the obtained compounds was performed using FTIR, 1D and 2D NMR.•DFT calculation study confirmed the structural stability of the obtained compounds.•New thiazole derivatives exhibited moderate antioxidant activity, while their antibacterial one was much more interesting against some bacterial strains.•Molecular docking study revealed that the new thiazole derivatives can be good candidates to inhibit TNF-α.
More
Translated text
Key words
Hemi-synthesis,Perillaldehyde,Cuminaldehyde,Essential oil,2D NMR,Fluorescence,Biological activity,Molecular docking
AI Read Science
Must-Reading Tree
Example
Generate MRT to find the research sequence of this paper
Chat Paper
Summary is being generated by the instructions you defined