Metal-catalyzed synthesis of triazine derivatives

Heterocycles, primarily the nitrogen-containing six-membered triazines, pyrimidines, and pyridines are used in synthesizing the active pharmaceutical synthons and natural products. Catalysis, particularly transition metal catalysis, can also be used to obtain regioselective, stereoselective, and chemoselective transformations. This review work deals with the recent advances made in metal-mediated/catalyzed synthesis of triazine derivatives and therefore will assist chemists in comprehending the issues associated with the present methods as well as future prospects, in terms of substrate and catalyst respectively. This article is of interest to a large area of organic chemists working in the field of heterocyclic productions in academia and industrial R&D sectors. Noteworthy, this assessment will serve as a guiding light to consider: (i) the importance of several transition metals employed in the method development domain and (ii) in the R&D sector for further necessary modifications. Graphical abstract