Transcatheter Edge-to-Edge Repair in Patients with Severe Mitral Regurgitation and Cardiogenic Shock: TVT Registry Analysis.

We examined the role of transcatheter edge-to-edge repair (TEER) in patients with cardiogenic shock and mitral regurgitation (MR). We identified 3,797 patients with cardiogenic shock who underwent TEER between 2013-2021 in the STS/ACC/TVT registry. Mean age was 73.0±11.9 and 59.5% were males. Mean STS was 14.9±15.3. Device success (defined as MR reduction of >1 grade and a final MR <2+) was achieved in 3,249 patients (85.6%). At one-year, device success was associated with lower all-cause mortality (34.6% vs.55.5%,adjusted-HR 0.49,95%CI 0.41-0.58, p<0.001), and a composite of mortality and HF admissions (29.6% vs. 45.2%, adjusted HR 0.51,95%CI 0.42-0.62, p<0.001).