Three new coumarin derivatives from Maytenus hookeri

Lingjie Meng,Changyan Yu,Jing Hui,Nian Jiang,Haijuan Wang,Jianxun Xie,Lin Xu,Yun Liu

NATURAL PRODUCT RESEARCH（2024）

引用 0|浏览4

暂无评分

摘要

Three new coumarin derivatives named maytenucoums A-C (1-3), along with six known analogs (4-9), were isolated from the branches of Maytenus hookeri. Their structures were determined by comprehensive spectroscopic data analysis, including NMR and HR-ESIMS. In the preliminary assays, compound 4 showed cytotoxic activity against the A549, SK-Hep1 and HCT116 cells with IC50 values of 29.0, 28.6 and 54.4 mu M, respectively.

查看译文

关键词

Maytenus hookeri,coumarin derivatives,maytenucoums A-C,cytotoxic activity

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要