MiR-590-3p affects the function of adipose-derived stem cells (ADSCs) on the survival of skin flaps by targeting VEGFA

Kai Yang,Xiancheng Wang, Yang Sun,Xiang Xiong,Xianxi Meng,Bairong Fang,Wenbo Li,Zhongjie Yi

Regenerative Therapy（2022）

引用 1|浏览7

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摘要

•ADSCs transplantation improve perforator flap survival.•Agomir-590-3p transfected ADSCs inhibited perforator flap survival.•MiR-590-3p targeted VEGFA 3′UTR to regulate its expression.•The miR-590-3p/VEGFA axis in ADSCs modulates skin flap angiogenesis.

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关键词

Skin flap,Adipose-derived stem cells,Flap survival,miR-590-3p,VEGFA

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