Impact of Fluoroquinolone Prophylaxis on Neutropenic Fever, Infections, and Antimicrobial Resistance in Newly Diagnosed AML Patients.

Jessica Caro,Rafael Madero-Marroquin,Nicole Zubizarreta,Erin Moshier,Douglas Tremblay,Alex Coltoff,Guido Lancman,Risa Fuller,Meenakshi Rana,John Mascarenhas,Samantha E Jacobs

Clinical lymphoma, myeloma & leukemia（2022）

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摘要

In an area with high fluoroquinolone resistance, primary fluoroquinolone prophylaxis in newly diagnosed AML patients reduced the risk of neutropenic fever and systemic bacterial infections without increased antimicrobial resistance. Prospective, randomized studies are needed to confirm these observations.

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关键词

AML,Acute myeloid leukemia,Antibiotic resistance,Fluoroquinolone,Infection,Leukemia

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