Study on Integrated Pharmacokinetics of the Component-Based Chinese Medicine of Ginkgo biloba Leaves Based on Nanocrystalline Solid Dispersion Technology.

International journal of nanomedicine(2022)

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Abstract
This study demonstrated that novel GBCCM NC-SD was prepared using Polyvinylpyrrolidone K30 (PVP K30) and Sodium dodecyl sulfate (SDS) as a synergetic stabilizer and also provided a feasible way to improve the dissolution and oral bioavailability of poorly soluble candidate antihypertensive drugs.
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Key words
Ginkgo biloba,charged aerosol detector,flavonoid aglycones,integrated pharmacokinetics,nanocrystalline solid dispersion,terpenoid lactones
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