Serum Uromodulin in Children and Adolescents with Type 1 Diabetes Mellitus and Controls: Its Potential Role in Kidney Health.

Ralf Schiel, Mathias Block,Antje Steveling,Günter Stein, Sarah Lücking,Jürgen Scherberich

Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association（2023）

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摘要

Our study shows that children/adolescents with type 1 diabetes disclose similar sUMOD concentrations as healthy controls. Serum UMOD appears to indicate higher risks for kidney tissue remodeling and possibly subsequent cardiovascular alterations. However, further studies are mandatory to settle these findings.

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关键词

Serum uromodulin,ELISA,kidney biomarker,juvenile type 1 diabetes,risk assessment

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