WNT5A-RHOA Signaling Is a Driver of Tumorigenesis and Represents a Therapeutically Actionable Vulnerability in Small Cell Lung Cancer.

Kee-Beom Kim,Dong-Wook Kim,Youngchul Kim,Jun Tang,Nicole Kirk,Yongyu Gan,Bongjun Kim,Bingliang Fang,Jae-Ll Park,Yi Zheng,Kwon-Sik Park

Cancer research（2022）

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摘要

The p130-WNT5A-RHOA pathway drives SCLC progression and is a potential target for the development of therapeutic interventions and biomarkers to improve patient treatment.

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关键词

small cell lung cancer,wnt5a–rhoa signaling,cell lung cancer,lung cancer,tumorigenesis

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