Simvastatin Upregulates Lipoxin A4 and Accelerates Neuroinflammation Resolution After Intracerebral Hemorrhage.
Current neurovascular research(2022)
摘要
Collectively, these results suggest that simvastatin ameliorates ICH-mediated inflammatory brain injury, possibly by upregulating the level of pro-resolving mediator LXA4 and further stimulating the FPR2/p38 MAPK signaling pathway.
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关键词
Intracerebral hemorrhage,apoptosis,formyl-peptide receptor 2,inflammation,lipoxin A4,neutrophils,statins
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