The Outcome of Daily Low Dose of Tadalafil in Diabetic Men with Erectile Dysfunction

Background: Men with diabetes mellitus frequently experience erectile dysfunction (ED).Objective: The purpose of this study is to determine whether or not 5 mg of tadalafil daily is effective in treating erectile dysfunction in men who are diabetic.Patients and methods: In this trial, 50 diabetic males with ED were given 5 mg of tadalafil once daily for 12 weeks.Using the International Index of Erectile Function (IIEF) and penis-specific Color Duplex Doppler Ultrasonography, researchers evaluated tadalafil's effects on erection quality and duration.Results: Age of 45 was the median, and the average body mass index was 30.3 kg/m², 54 % of them were smokers.We found statistical significant (p-value < 0.001) increased 12 weeks IIEF score (median = 18.5, IQR = 13 -22) when compared baseline IIEF score (median = 12.4,IQR = 10 -17).Our results showed statistical significant (pvalue < 0.001) increased 12 weeks PSV (median = 36, IQR = 35 -37) when compared with baseline PSV (median = 33, IQR = 30 -35).Using multivariate logistic regression analysis, we demonstrated that smoking, BMI, dyslipidemia and bad glycemic control were predictive factors for ED severity.Conclusion: Taking 5 milligrams of tadalafil once a day may help diabetic men's erectile dysfunction.