A Randomized, Placebo-Controlled Study of Methotrexate to Increase Response Rates in Patients with Uncontrolled Gout Receiving Pegloticase: Primary Efficacy and Safety Findings.

John K Botson,Kenneth Saag,Jeff Peterson,Naval Parikh,Stephen Ong,Dan La,Karon LoCicero,Katie Obermeyer,Yan Xin,Jason Chamberlain,Brian LaMoreaux,Supra Verma,Stephen Sainati,Suneet Grewal,Amar Majjhoo,John R P Tesser,Michael E Weinblatt

Arthritis & rheumatology (Hoboken, N.J.)（2023）

引用 9|浏览24

暂无评分

摘要

MTX cotherapy markedly increased pegloticase response rate over placebo (71.0% versus 38.5%) during month 6 with no new safety signals. These findings verify higher treatment response rate, lower infusion reaction incidence, and lower immunogenicity when pegloticase is coadministered with MTX.

查看译文

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要