Cannabidiol prevents chemotherapy-induced neuropathic pain by modulating spinal TLR4 via endocannabinoid system activation.
The Journal of pharmacy and pharmacology(2023)
摘要
CBD was efficient in preventing PTX-induced neuropathic pain, and this effect may involve inhibition of the TLR4 on microglia spinal with activation of the endocannabinoid system.
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关键词
cannabidiol,glial cells,neuropathic pain,pro-inflammatory cytokines
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