Fluorescence Lifetime Imaging of Protein Aggregation to Understand the Etiology of Neurodegenerative Diseases

Paula-Marie E. Ivey,Arjun Krishnamoorthi,Sehong Min,Jean-Christophe Rochet,Kevin J. Webb

Conference on Lasers and Electro-Optics（2022）

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摘要

Time-domain fluorescence lifetime imaging microscopy is presented for the detection of alpha-synuclein aggregation in neurons and for determining spread, thereby facilitating understanding of the development and progression of Parkinson’s disease.

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关键词

protein aggregation,fluorescence,imaging

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